WebAug 23, 2024 · Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It’s an evolutionary self-preservation mechanism … WebChaperone Mediated Autophagy (CMA) is a lysosomal-dependent protein degradation pathway. At least 30% of cytosolic proteins can be degraded by this process. The two major protein players of CMA are LAMP-2A and …
Tissue expression of RCAN1 - Summary - The Human Protein Atlas
WebDec 15, 2024 · DUSP1 inhibits autophagy-dependent ferroptosis. Autophagy is a conserved mechanism to degrade cellular molecules and organelles to sustain homeostasis. … WebNov 5, 2014 · Hence, we analyzed the effect of Rcan1-1L overexpression on autophagy flux. We found that markers of autophagy, LC3 II and autophagy related gene (ATG) 5 (Klionsky et al., 2012), were highly upregulated by Rcan1-1L overexpression, which was further increased by the lysosome inhibitor chloroquine (Klionsky et al., 2012) (Fig. 6A). order form in excel
Chronic Expression of RCAN1-1L Protein Induces …
WebDec 2, 2024 · The RCAN1 gene is located in the q22.1–q22.2 region of human chromosome 21 and is expressed primarily in the brain, heart, skeletal muscle and endocrine tissues … WebRCAN1 proteins have both protective and harmful effects, and are implicated in common human pathologies. The mechanisms by which RCAN1s function, however, remain poorly … WebJun 18, 2024 · Cancer is the leading cause of mortality worldwide. Regulator of calcineurin 1 (RCAN1), as a patent endogenous inhibitor of calcineurin, plays crucial roles in the … order form for t shirts template free